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**Õ ϸ°ûµòÍö **½Ú µòÍö·¢ÉúµÄ»úÖÆ µÚ¶þ½Ú µòÍöϸ°ûµÄÐÎ̬ÌØÕ÷ µÚÈý½Ú ¼²²¡ÖеòÍöµÄÑо¿ µÚËÄ½Ú µòÍöµÄ¼ì²â·½·¨ ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter1 Apoptosis Section1 Mechanism of Apoptosis Section2 Morphology of Apoptosis Section3 Apoptosis and Diseases Section4 Detection Methods of Apoptosis Challenges and Prospects Consider/Questions µÚ¶þÕ ϸ°û×ÔÊÉ **½Ú ϸ°û×ÔÊɵÄÐÎ̬ѧºÍ·¢Éú¹ý³Ì µÚ¶þ½Ú ×ÔÊÉÏà¹Ø»ùÒò µÚÈý½Ú ×ÔÊÉÓëÆäËûϸ°ûʼþµÄ¹Øϵ µÚËÄ½Ú Õë¶Ô×ÔÊɵÄÒ©Îï°Ðµã µÚÎå½Ú Ñо¿×ÔÊɵķ½·¨ ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter2 Cell Autophagy¡ª¡ª¡°Self-Eating¡± Section1 Morphology and Process of Cell Autophagy Section2 Autophagy Associated Genes Section3 Relationship of Autophagy and Other Cellular Events Section4 Pharmacologic Targets to Autophagy System Section5 Studying Methods of Autophagy Challenges and Prospects Consider/Questions µÚÈýÕ ϸ°ûÄÚÍÌ **½Ú ÄÚÍÌ×÷ÓõÄÀàÐͺͻúÖÆ µÚ¶þ½Ú ÄÚÍ̵°°×µÄÌØÕ÷ µÚÈý½Ú ÄÚÍÌͨ·ÖеĹؼüµ°°× µÚËÄ½Ú ÄÚÍ̶ÔÖÊĤÐźŵĵ÷¿Ø µÚÎå½Ú ÄÚÍÌ×÷ÓõÄÒâÒå ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter3 Cell Endocytosis Section1 Types and Mechanisms of Endocytosis Section2 Features of Endophilin Section3 Key Proteins in Endocytic Pathways Section4 Endocytosis Regulates Plasma Membrane Signalling Section5 Significance in Endocytosis Challenges and Prospects Consider/Questions µÚËÄÕ ϸ°û𤸽·Ö×Ó **½Ú CAMµÄ¸ÅÊö µÚ¶þ½Ú ÕûºÏËس¬¼Ò×å µÚÈý½Ú ÃâÒßÇòµ°°×³¬¼Ò×å µÚËÄ½Ú Ñ¡ÔñËؼÒ×å µÚÎå½Ú ¸Æð¤×ŵ°°×¼Ò×å µÚÁù½Ú ÆäËûδ¹éÀàµÄ𤸽·Ö×Ó ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter4 Cell Adhesion Molecules Section1 Outlines of Cell Adhesion Molecules Section2 Integrin Superfamily Section3 Immunoglobulin Superfamily (Ig-SF) Section4 Selectin Family Section5 Cadherin Family Section6 Unclassified CAM Challenges and Prospects Consider/Questions µÚÎåÕ ϸ°ûÖÜÆڵĵ÷¿Ø **½Ú ϸ°ûÖÜÆڵĻù±¾¸ÅÄî µÚ¶þ½Ú ϸ°ûÖÜÆÚµ÷¿ØÖеÄÖØÒªÔªËØ µÚÈý½Ú ϸ°ûÖÜÆÚµ÷¿ØÖи÷ÔªËؼäµÄÏ໥×÷Óà µÚËÄ½Ú Ï¸°ûÖÜÆÚ¼ì²âµã µÚÎå½Ú ϸ°ûÖÜÆڵĵ÷¿ØÓëÖ×Áö ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter5 Cell Cycle Regulation Section1 Conception of Cell Cycle Section2 Important Factors in Cell Cycle Regulation Section3 Interaction of Various Elements in Cell Cycle Section4 Cell Cycle Checkpoints Section5 Cell Cycle Regulation in Human Cancer Research and Treatment Challenges and Prospects Consider/Questions µÚÁùÕ ¶ËÁ£Óë¶ËÁ£Ã¸ **½Ú ¶ËÁ£Óë¶ËÁ£Ã¸µÄ·¢ÏÖ µÚ¶þ½Ú ¶ËÁ£Óë¶ËÁ£Ã¸µÄÌØÕ÷ µÚÈý½Ú ¶ËÁ£Óë¶ËÁ£Ã¸µÄ×÷ÓûúÖÆ µÚËÄ½Ú ¼²²¡ÖжËÁ£Óë¶ËÁ£Ã¸Ñо¿µÄÒâÒå µÚÎå½Ú ÒÔ¶ËÁ£Ã¸Îª°Ð±êµÄ¿¹°©Ò©ÎïÑо¿ µÚÁù½Ú ¼ì²â¶ËÁ£Ã¸µÄ·½·¨ ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter6 Telomere and Telomerase Section1 Discovery of Telomere and Telomerase Section2 Structure and Functions of Telomere and Telomerase Section3 Role Mechanism of Telomere and Telomerase Section4 Studies of Telomere-telomerase in Diseases Section5 Telomerase as A Target for Anti-cancers Section6 Detection Methods for Telomerase Challenges and Prospects Consider/Questions µÚÆßÕ Ö×Áö¸Éϸ°û **½Ú ¸Éϸ°û µÚ¶þ½Ú ÅßÌ¥¸Éϸ°û µÚÈý½Ú ³ÉÌå¸Éϸ°û µÚËÄ½Ú Ö×Áö¸Éϸ°û ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter7 Cancer Stem Cells Section1 Introduction for Stem Cells Section2 Embryonic Stem Cells Section3 Adult Stem Cells Section4 Cancer Stem Cells Challenges and Prospects Consider/Questions µÚ°ËÕ ϸ°ûÐźÅתµ¼Í¾¾¶ **½Ú ¹¹³Éϸ°ûÐźÅתµ¼ÏµÍ³µÄÒªËØ µÚ¶þ½Ú ϸ°ûĤ±íÃæÊÜÌå½éµ¼µÄÐźÅתµ¼Í¾¾¶ µÚÈý½Ú ϸ°û°ûÄÚÊÜÌå½éµ¼µÄÐźÅתµ¼Í¾¾¶ µÚËÄ½Ú ¿É¿ØÐÔµ°°×½µ½âµÄÐźÅתµ¼Í¾¾¶ µÚÎå½Ú ϸ°ûÐźÅתµ¼µÄÌص㼰ÆäÏ໥×÷Óà µÚÁù½Ú ϸ°ûÐźÅתµ¼ÕÏ°­ÓëÖ×Áö ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter8 Cell Communication & Signaling Section1 Elements of Cell Signal Transduction System Section2 Cell Signal Transduction Mediated by Membrane Surface Receptor Section3 Cell Signal Transduction Mediated by Intracellular Receptor Section4 Controllable Protein Degradation and Cell Signal Transduction Section5 Characteristics of Cell Signal Transduction Section6 Signal Transduction Disorders and Tumors Challenges and Prospects Consider/Questions µÚ¾ÅÕ Ö×ÁöѪ¹ÜÐÎ³É **½Ú Õý³£Ñª¹ÜÐÎ³É µÚ¶þ½Ú Ö×ÁöѪ¹ÜÐÎ³É µÚÈý½Ú Ö×ÁöÐÂÉúѪ¹ÜµÄÌص㠵ÚËÄ½Ú µ÷¿ØÖ×ÁöѪ¹ÜÐγɵÄÒòËØ µÚÎå½Ú ¿¹Ö×ÁöѪ¹ÜÐγɵÄÑо¿ ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter9 Tumor Angiogenesis Section1 Angiogenesis Section2 Tumor Angiogenesis Section3 Characteristics of Tumor Angiogenesis Section4 Regulating Factors of Angiogenesis Section5 Anti-angiogenesis¡ªCurrent Research and Clinical Implications Challenges and Prospects Consider/Questions µÚʮՠÉÏƤ¼äÖÊת»¯£¨EMT£© **½Ú ÅßÌ¥·¢ÓýÏà¹ØµÄEMT µÚ¶þ½Ú ×éÖ¯ËðÉ˺ÍÏËά»¯Ïà¹ØµÄEMT µÚÈý½Ú °©½øÕ¹ºÍתÒÆÏà¹ØµÄEMT µÚËÄ½Ú µ÷¿ØEMTµÄ·Ö×Ó»úÖÆ ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter10 Epithelial Mesenchymal Transition (EMT) Section1 EMT in Embryonic Development Section2 EMT in Tissue Regeneration and Organ Fibrosis Section3 EMT in Tumor Progression and Metastasis Section4 Molecule Mechanism of Regulating EMT Challenges and Prospects Consider/Questions µÚʮһÕ Ö×ÁöÇÖÏ®ÓëתÒÆ **½Ú Ö×ÁöתÒƸÅÊö µÚ¶þ½Ú Áöϸ°û𤸽ÄÜÁ¦¸Ä±ä µÚÈý½Ú ½µ½âECMµÄµ°°×Ë®½âø µÚËÄ½Ú Ö×Áöϸ°ûǨÒƶ¯Á¦ µÚÎå½Ú Ö×ÁöתÒƵĻùÒòµ÷¿Ø µÚÁù½Ú Ö×ÁöתÒÆÖеÄÐźÅתµ¼Í¨Â· ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter11 Tumor Invasion and Metas-tasis Section1 Concepts of Tumor Metastasis Section2 Adhesion of Tumor Cells Section3 Proteolytic Enzymes Degrading ECM Section4 Enhancement of Tumor Mobility Section5 Regulation of Tumor Metastasis Section6 Signal Pathways in Tumor Metastasis Challenges and Prospects Consider/Questions µÚÊ®¶þÕ ±í¹ÛÒÅ´«Ñ§¸Ä±ä **½Ú ±í¹ÛÒÅ´«Ñ§µÄ¸ÅÄî µÚ¶þ½Ú ±í¹ÛÒÅ´«Ñ§µÄÖ÷ÒªÄÚÈÝ µÚÈý½Ú ÔÚ¼²²¡Öбí¹ÛÒÅ´«Ñ§¸Ä±äµÄÒâÒå ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter12 Epigenetic Changes Section1 Concepts of Epigenetics Section2 Main Content of Epigenetics Section3 Significance of Epigenetic Changes in Diseases Challenges and Prospects Consider/Questions µÚÊ®ÈýÕ Ö×Áö΢»·¾³ **½Ú TMEÖÐѪÑõ¸Ä±ä µÚ¶þ½Ú TMEÖеÄϸ°û³É·Ö µÚÈý½Ú ϸ°ûÍâ»ùÖÊÖØËÜ µÚËÄ½Ú Ö×Áöϸ°ûºÍTMEÖ®¼äͨÐÅ ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter13 Tumor Microenvironment Section1 Vascular and Metabolic Changes in TME Section2 Cellular Components in TME Section3 Extracellular Matrix Remodeling Section4 Communication between Tumor Cells and TME Section5 Clinical Implications Challenges and Perspectives Consider/Questions µÚÊ®ËÄÕ Ö×ÁöµÄ°ÐÏòÐÔÖÎÁÆ **½Ú ·Ö×Ó²¡ÀíѧÔÚÖ×Áö°ÐÏòÖÎÁÆÖеÄ×÷Óà µÚ¶þ½Ú ³£ÓõķÖ×Ӱе㼰°ÐÏòÒ©Îï µÚÈý½Ú ³£¼ûÖ×ÁöµÄ·Ö×Ó°ÐÏòÖÎÁÆ ÌôÕ½ÓëÕ¹Íû ˼¿¼Ì⠲ο¼ÎÄÏ× Chapter14 Targeted Therapy for Tumor Section1 Roles of Molecular Pathology in Targeted Therapy of Tumors Section2 Common Used Molecular Targets and Targeted Drugs Section3 Molecular Targeted Therapy in Common Tumors Challenges and Prospects Consider/Questions